CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.70.100
Functional Family (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase

Enzyme Information

5.3.1.32
(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase.
based on mapping to UniProt D3QT67
(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione = 3-hydroxy-5- phosphonooxypentane-2,4-dione.
-!- The enzyme participates in a degradation pathway of the bacterial quorum-sensing autoinducer molecule AI-2.

UniProtKB Entries (1)

D3QT67
D3QT67_ECOCB
Escherichia coli O55:H7 str. CB9615
(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase

PDB Structure

PDB 3QMQ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Processing the Interspecies Quorum-sensing Signal Autoinducer-2 (AI-2): CHARACTERIZATION OF PHOSPHO-(S)-4,5-DIHYDROXY-2,3-PENTANEDIONE ISOMERIZATION BY LsrG PROTEIN.
Marques, J.C., Lamosa, P., Russell, C., Ventura, R., Maycock, C., Semmelhack, M.F., Miller, S.T., Xavier, K.B.
J.Biol.Chem.