CATH Classification

Domain Context

CATH Clusters

Superfamily 5' to 3' exonuclease, C-terminal subdomain
Functional Family exonuclease 1

Enzyme Information

3.1.-.-
Acting on ester bonds.
based on mapping to UniProt Q9UQ84

UniProtKB Entries (1)

Q9UQ84
EXO1_HUMAN
Homo sapiens
Exonuclease 1

PDB Structure

PDB 3QEB
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structures of human exonuclease 1 DNA complexes suggest a unified mechanism for nuclease family.
Orans, J., McSweeney, E.A., Iyer, R.R., Hast, M.A., Hellinga, H.W., Modrich, P., Beese, L.S.
Cell(Cambridge,Mass.)