CATH Classification

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family tyrosine-protein phosphatase Lar isoform X3

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt P16621
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

P16621
LAR_DROME
Drosophila melanogaster
Tyrosine-protein phosphatase Lar

PDB Structure

PDB 3PXJ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The Immunoglobulin-like Domains 1 and 2 of the Protein Tyrosine Phosphatase LAR Adopt an Unusual Horseshoe-like Conformation.
Biersmith, B.H., Hammel, M., Geisbrecht, E.R., Bouyain, S.
J.Mol.Biol.