CATH Classification

Domain Context

CATH Clusters

Superfamily Cytochrome c1, transmembrane anchor, C-terminal
Functional Family UDP-glucose 6-dehydrogenase

Enzyme Information

1.1.1.22
UDP-glucose 6-dehydrogenase.
based on mapping to UniProt O60701
UDP-glucose + 2 NAD(+) + H(2)O = UDP-glucuronate + 2 NADH.
-!- Also acts on UDP-2-deoxyglucose.

UniProtKB Entries (1)

O60701
UGDH_HUMAN
Homo sapiens
UDP-glucose 6-dehydrogenase

PDB Structure

PDB 3PTZ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Role of Packing Defects in the Evolution of Allostery and Induced Fit in Human UDP-Glucose Dehydrogenase.
Kadirvelraj, R., Sennett, N.C., Polizzi, S.J., Weitzel, S., Wood, Z.A.
Biochemistry