1 keywords

CATH Domain 3pqzA00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.30 2-Layer Sandwich
Topology 3.30.505 SHC Adaptor Protein
Homologous Superfamily 3.30.505.10 SH2 domain

Domain Context

CATH Clusters

Superfamily SH2 domain
Functional Family Growth factor receptor-bound protein 10 isoform X1

Enzyme Information

UniProtKB Entries (1)

Q14451
GRB7_HUMAN
Homo sapiens
Growth factor receptor-bound protein 7

PDB Structure

PDB 3PQZ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis of binding by cyclic nonphosphorylated Peptide antagonists of grb7 implicated in breast cancer progression
Ambaye, N.D., Pero, S.C., Gunzburg, M.J., Yap, M., Clayton, D.J., Del Borgo, M.P., Perlmutter, P., Aguilar, M.I., Shukla, G.S., Peletskaya, E., Cookson, M.M., Krag, D.N., Wilce, M.C., Wilce, J.A.
J.Mol.Biol.