CATH Domain 3pmxA01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.190	D-Maltodextrin-Binding Protein; domain 2
	3.40.190.10	Periplasmic binding protein-like II

Domain Context

CATH Clusters

Superfamily	Periplasmic binding protein-like II
Functional Family	Glutamate receptor ionotropic, kainate 2

Enzyme Information

UniProtKB Entries (1)

GRIA2_RAT

Rattus norvegicus

Glutamate receptor 2

PDB Structure

PDB	3PMX
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure based evolution of a novel series of positive modulators of the AMPA receptor. Jamieson, C., Maclean, J.K., Brown, C.I., Campbell, R.A., Gillen, K.J., Gillespie, J., Kazemier, B., Kiczun, M., Lamont, Y., Lyons, A.J., Moir, E.M., Morrow, J.A., Pantling, J., Rankovic, Z., Smith, L. Bioorg.Med.Chem.Lett.