CATH Classification

Domain Context

CATH Clusters

Superfamily Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Functional Family Rho guanine nucleotide exchange factor 1

Enzyme Information

UniProtKB Entries (1)

Q92888
ARHG1_HUMAN
Homo sapiens
Rho guanine nucleotide exchange factor 1

PDB Structure

PDB 3ODW
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Modulation of a GEF switch: Autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoREF
Chen, Z., Guo, L., Sprang, S.R., Sternweis, P.C.
Protein Sci.