CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.367.20
Functional Family Phosphotransferase

Enzyme Information

2.7.1.1
Hexokinase.
based on mapping to UniProt P33284
ATP + D-hexose = ADP + D-hexose 6-phosphate.
-!- D-glucose, D-mannose, D-fructose, sorbitol and D-glucosamine can act as acceptors. -!- ITP and dATP can act as donors.

UniProtKB Entries (1)

P33284
HXK_KLULA
Kluyveromyces lactis NRRL Y-1140
Hexokinase

PDB Structure

PDB 3O80
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of Hexokinase KlHxk1 of Kluyveromyces lactis: A MOLECULAR BASIS FOR UNDERSTANDING THE CONTROL OF YEAST HEXOKINASE FUNCTIONS VIA COVALENT MODIFICATION AND OLIGOMERIZATION.
Kuettner, E.B., Kettner, K., Keim, A., Svergun, D.I., Volke, D., Singer, D., Hoffmann, R., Muller, E.C., Otto, A., Kriegel, T.M., Strater, N.
J.Biol.Chem.