CATH Classification

Domain Context

CATH Clusters

Superfamily 2.80.10.50
Functional Family

Enzyme Information

3.2.2.22
rRNA N-glycosylase.
based on mapping to UniProt P81446
Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA.
-!- Ricin A-chain and related toxins show this activity. -!- Naked rRNA is attacked more slowly than rRNA in intact ribosomes. -!- Naked rRNA from Escherichia coli is cleaved at a corresponding position.

UniProtKB Entries (1)

P81446
ML1_VISAL
Viscum album
Beta-galactoside-specific lectin 1

PDB Structure

PDB 3O5W
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Binding of the plant hormone kinetin in the active site of Mistletoe Lectin I from Viscum album.
Malecki, P.H., Rypniewski, W., Szymanski, M., Barciszewski, J., Meyer, A.
Biochim.Biophys.Acta