CATH Classification

Domain Context

CATH Clusters

Superfamily Trypsin-like serine proteases
Functional Family

Enzyme Information

3.4.21.-
Serine endopeptidases.
based on mapping to UniProt Q92743

UniProtKB Entries (2)

Q9CZU6
CISY_MOUSE
Mus musculus
Citrate synthase, mitochondrial
Q92743
HTRA1_HUMAN
Homo sapiens
Serine protease HTRA1

PDB Structure

PDB 3NZI
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Substrate-induced remodeling of the active site regulates human HTRA1 activity.
Truebestein, L., Tennstaedt, A., Monig, T., Krojer, T., Canellas, F., Kaiser, M., Clausen, T., Ehrmann, M.
Nat.Struct.Mol.Biol.