1 keywords

CATH Domain 3nepX02

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.90 Alpha-Beta Complex
Topology 3.90.110 L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2
Homologous Superfamily 3.90.110.10 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal

Domain Context

CATH Clusters

Superfamily Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
Functional Family Malate dehydrogenase

Enzyme Information

1.1.1.37
Malate dehydrogenase.
based on mapping to UniProt Q2S289
(S)-malate + NAD(+) = oxaloacetate + NADH.
-!- Also oxidizes some other 2-hydroxydicarboxylic acids.

UniProtKB Entries (1)

Q2S289
MDH_SALRD
Salinibacter ruber DSM 13855
Malate dehydrogenase

PDB Structure

PDB 3NEP
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Gradual adaptive changes of a protein facing high salt concentrations.
Coquelle, N., Talon, R., Juers, D.H., Girard, E., Kahn, R., Madern, D.
J.Mol.Biol.