CATH Classification

Domain Context

CATH Clusters

Superfamily DnaQ-like 3'-5' exonuclease
Functional Family DNA-directed DNA polymerase

Enzyme Information

2.7.7.7
DNA-directed DNA polymerase.
based on mapping to UniProt Q38087
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.
3.1.11.-
Exodeoxyribonucleases producing 5'-phosphomonoesters.
based on mapping to UniProt Q38087

UniProtKB Entries (1)

Q38087
DPOL_BPR69
Enterobacteria phage RB69
DNA-directed DNA polymerase

PDB Structure

PDB 3NE6
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Variation in Mutation Rates Caused by RB69pol Fidelity Mutants Can Be Rationalized on the Basis of Their Kinetic Behavior and Crystal Structures.
Xia, S., Wang, M., Lee, H.R., Sinha, A., Blaha, G., Christian, T., Wang, J., Konigsberg, W.
J.Mol.Biol.