CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family Probable ATP-citrate synthase

Enzyme Information

2.3.3.8
ATP citrate synthase.
based on mapping to UniProt P53396
ADP + phosphate + acetyl-CoA + oxaloacetate = ATP + citrate + CoA.
-!- The enzyme can be dissociated into components, two of which are identical with EC 4.1.3.34 and EC 6.2.1.18. -!- Formerly EC 4.1.3.8.

UniProtKB Entries (1)

P53396
ACLY_HUMAN
Homo sapiens
ATP-citrate synthase

PDB Structure

PDB 3MWD
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Identification of the citrate-binding site of human ATP-citrate lyase using X-ray crystallography.
Sun, T., Hayakawa, K., Bateman, K.S., Fraser, M.E.
J.Biol.Chem.