CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.70.270
Functional Family DNA polymerase IV

Enzyme Information

2.7.7.7
DNA-directed DNA polymerase.
based on mapping to UniProt Q97W02
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

Q97W02
DPO4_SACS2
Saccharolobus solfataricus P2
DNA polymerase IV

PDB Structure

PDB 3M9O
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural insight into dynamic bypass of the major cisplatin-DNA adduct by Y-family polymerase Dpo4.
Wong, J.H., Brown, J.A., Suo, Z., Blum, P., Nohmi, T., Ling, H.
Embo J.