CATH Classification

Domain Context

CATH Clusters

Superfamily alpha/beta hydrolase
Functional Family Cephalosporin-C deacetylase

Enzyme Information

3.1.1.72
Acetylxylan esterase.
based on mapping to UniProt Q9WXT2
Deacetylation of xylans and xylo-oligosaccharides.
-!- Catalyzes the hydrolysis of acetyl groups from polymeric xylan, acetylated xylose, acetylated glucose, alpha-napthyl acetate, p-nitrophenyl acetate but not from triacetylglycerol. -!- Does not act on acetylated mannan or pectin.
3.1.1.41
Cephalosporin-C deacetylase.
based on mapping to UniProt Q9WXT2
Cephalosporin C + H(2)O = deacetylcephalosporin C + acetate.
-!- Hydrolyzes the acetyl ester bond on the 10-position of the antibiotic cephalosporin C.

UniProtKB Entries (1)

Q9WXT2
CAH_THEMA
Thermotoga maritima MSB8
Cephalosporin-C deacetylase

PDB Structure

PDB 3M82
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Functional and structural characterization of a thermostable acetyl esterase from Thermotoga maritima.
Levisson, M., Han, G.W., Deller, M.C., Xu, Q., Biely, P., Hendriks, S., Ten Eyck, L.F., Flensburg, C., Roversi, P., Miller, M.D., McMullan, D., von Delft, F., Kreusch, A., Deacon, A.M., van der Oost, J., Lesley, S.A., Elsliger, M.A., Kengen, S.W., Wilson, I.A.
Proteins