CATH Classification

Domain Context

CATH Clusters

Superfamily 2.40.10.120
Functional Family

Enzyme Information

UniProtKB Entries (1)

Q9ELS8
Q9ELS8_9HEPC
Hepatitis C virus subtype 1a
Genome polyprotein

PDB Structure

PDB 3LON
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Candidate selection and preclinical evaluation culminating in the discovery of Narlaprevir (SCH 900518): A potent, selective and orally efficacious second generation HCV NS3 serine protease inhibitor
Arasappan, A., Bennett, F., Bogen, S.L., Blackman, M., Chen, K., Hendrata, S., Huang, Y., Huelgas, R.M., Nair, L., Padilla, A.I., Pan, W., Pike, R., Pinto, P., Ruan, S., Sannigrahi, M., Velaquez, F., Vibulbhan, B., Wu, W., Yang, W., Saksena, A.K., Girijavallabhan, V., Shih, N.Y., Kong, J., Meng, T., Jin, Y., Wong, J., McNamara, P., Prongay, A., Madison, V., Piwinski, J.J., Cheng, K.C., Morrison, R., Malcolm, B., Tong, X., Ralston, R., Njoroge, F.G.
To be Published