CATH Classification

Domain Context

CATH Clusters

Superfamily Collagenase (Catalytic Domain)
Functional Family A disintegrin and metalloproteinase with thrombospondin motifs 1

Enzyme Information

3.4.24.-
Metalloendopeptidases.
based on mapping to UniProt Q9UNA0

UniProtKB Entries (1)

Q9UNA0
ATS5_HUMAN
Homo sapiens
A disintegrin and metalloproteinase with thrombospondin motifs 5

PDB Structure

PDB 3LJT
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure analysis reveals the flexibility of the ADAMTS-5 active site.
Shieh, H.S., Tomasselli, A.G., Mathis, K.J., Schnute, M.E., Woodard, S.S., Caspers, N., Williams, J.M., Kiefer, J.R., Munie, G., Wittwer, A., Malfait, A.M., Tortorella, M.D.
Protein Sci.