CATH Classification

Domain Context

CATH Clusters

Superfamily DNA ligase/mRNA capping enzyme
Functional Family mRNA-capping enzyme subunit alpha

Enzyme Information

2.7.7.50
mRNA guanylyltransferase.
based on mapping to UniProt Q01159
GTP + (5')pp-Pur-mRNA = diphosphate + G(5')ppp-Pur-mRNA.
-!- Can modify also synthetic poly(A) and poly(G) to form the structures m(7)G(5')pppAn and m(7)G(5')pppGn.

UniProtKB Entries (1)

Q01159
MCE1_YEAST
Saccharomyces cerevisiae S288C
MRNA-capping enzyme subunit alpha

PDB Structure

PDB 3KYH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of the Saccharomyces cerevisiae Cet1-Ceg1 mRNA Capping Apparatus.
Gu, M., Rajashankar, K.R., Lima, C.D.
Structure