CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.240 | Tyrosyl-Transfer RNA Synthetase |
|
1.10.240.10 | Tyrosyl-Transfer RNA Synthetase |
Domain Context
CATH Clusters
| Superfamily | Tyrosyl-Transfer RNA Synthetase |
| Functional Family | Tryptophan--tRNA ligase, cytoplasmic |
Enzyme Information
| 6.1.1.2 |
Tryptophan--tRNA ligase.
based on mapping to UniProt Q12109
ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + L-tryptophyl- tRNA(Trp).
|
UniProtKB Entries (1)
| Q12109 |
SYWC_YEAST
Saccharomyces cerevisiae S288C
Tryptophan--tRNA ligase, cytoplasmic
|
PDB Structure
| PDB | 3KT0 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structures of Saccharomyces cerevisiae tryptophanyl-tRNA synthetase: new insights into the mechanism of tryptophan activation and implications for anti-fungal drug design
Nucleic Acids Res.
|