CATH Classification

Domain Context

CATH Clusters

Superfamily Type I PLP-dependent aspartate aminotransferase-like (Major domain)
Functional Family

Enzyme Information

2.6.1.51
Serine--pyruvate transaminase.
based on mapping to UniProt O35423
L-serine + pyruvate = 3-hydroxypyruvate + L-alanine.
-!- The liver enzyme may be identical with EC 2.6.1.44.
2.6.1.44
Alanine--glyoxylate transaminase.
based on mapping to UniProt O35423
L-alanine + glyoxylate = pyruvate + glycine.
-!- With one component of the animal enzyme, 2-oxobutanoate can replace glyoxylate. -!- A second component also catalyzes the reaction of EC 2.6.1.51.

UniProtKB Entries (1)

O35423
SPYA_MOUSE
Mus musculus
Serine--pyruvate aminotransferase, mitochondrial

PDB Structure

PDB 3KGW
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of Putative aminotransferase (AAH25799.1) from MUS MUSCULUS at 1.65 A resolution
Joint Center for Structural Genomics (JCSG)
To be published