CATH Classification

Domain Context

CATH Clusters

Superfamily Type I PLP-dependent aspartate aminotransferase-like (Major domain)
Functional Family Histidine decarboxylase

Enzyme Information

4.1.1.28
Aromatic-L-amino-acid decarboxylase.
based on mapping to UniProt P05031
(1) L-dopa = dopamine + CO(2). (2) 5-hydroxy-L-tryptophan = 5-hydroxytryptamine + CO(2).
-!- Also acts on other aromatic L-amino acids, including L-tryptophan. -!- Formerly EC 4.1.1.26 and EC 4.1.1.27.

UniProtKB Entries (1)

P05031
DDC_DROME
Drosophila melanogaster
Aromatic-L-amino-acid decarboxylase

PDB Structure

PDB 3K40
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure and substrate specificity of Drosophila 3,4-dihydroxyphenylalanine decarboxylase
Han, Q., Ding, H., Robinson, H., Christensen, B.M., Li, J.
Plos One