CATH Classification

Domain Context

CATH Clusters

Superfamily Alpha carbonic anhydrase
Functional Family Alpha carbonic anhydrase 3

Enzyme Information

4.2.1.1
Carbonic anhydrase.
based on mapping to UniProt P00918
H(2)CO(3) = CO(2) + H(2)O.
-!- The enzyme catalyzes the reversible hydration of gaseous CO(2) to carbonic acid, which spontaneously converts to hydrogencarbonate under neutral pH. -!- It is widespread and found in archaea, bacteria, and eukaryotes. -!- Three distinct classes exist, and appear to have evolved independently.

UniProtKB Entries (1)

P00918
CAH2_HUMAN
Homo sapiens
Carbonic anhydrase 2

PDB Structure

PDB 3K34
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Atomic resolution studies of carbonic anhydrase II.
Behnke, C.A., Le Trong, I., Godden, J.W., Merritt, E.A., Teller, D.C., Bajorath, J., Stenkamp, R.E.
Acta Crystallogr.,Sect.D