CATH Classification

Domain Context

CATH Clusters

Superfamily DD-peptidase/beta-lactamase superfamily
Functional Family

Enzyme Information

3.5.2.6
Beta-lactamase.
based on mapping to UniProt P13661
A beta-lactam + H(2)O = a substituted beta-amino acid.
-!- Zinc is only requires in class-B enzymes. -!- A group of enzymes of varying specificity hydrolyzing beta-lactams; some act more rapidly on penicillins, some more rapidly on cephalosporins. -!- Formerly EC 3.5.2.8.

UniProtKB Entries (1)

P13661
BLO1_ECOLX
Escherichia coli
Beta-lactamase OXA-1

PDB Structure

PDB 3ISG
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The 1.4 A crystal structure of the class D beta-lactamase OXA-1 complexed with doripenem.
Schneider, K.D., Karpen, M.E., Bonomo, R.A., Leonard, D.A., Powers, R.A.
Biochemistry