CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.91 | Restriction Endonuclease |
|
3.40.91.80 |
Domain Context
CATH Clusters
| Superfamily | 3.40.91.80 |
| Functional Family |
Enzyme Information
| 3.1.21.4 |
Type II site-specific deoxyribonuclease.
based on mapping to UniProt P14633
Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.
-!- Large group of enzymes which recognize specific short DNA sequences and cleave either within, or at a short specific distance from, the recognition site. -!- See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/
|
UniProtKB Entries (1)
| P14633 |
T2E2_ECOLX
Escherichia coli
Type-2 restriction enzyme EcoRII
|
PDB Structure
| PDB | 3HQG |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural mechanisms for the 5'-CCWGG sequence recognition by the N- and C-terminal domains of EcoRII.
Nucleic Acids Res.
|