CATH Classification

Domain Context

CATH Clusters

Superfamily Acyl-CoA thioester hydrolase/BAAT N-terminal domain
Functional Family acyl-coenzyme A thioesterase 4

Enzyme Information

3.1.2.2
Palmitoyl-CoA hydrolase.
based on mapping to UniProt P49753
Palmitoyl-CoA + H(2)O = CoA + palmitate.
-!- Also hydrolyzes CoA thioesters of other long-chain fatty acids.

UniProtKB Entries (1)

P49753
ACOT2_HUMAN
Homo sapiens
Acyl-coenzyme A thioesterase 2, mitochondrial

PDB Structure

PDB 3HLK
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of human mitochondrial acyl-CoA thioesterase (ACOT2)
Mandel, C.R., Tweel, B., Tong, L.
Biochem.Biophys.Res.Commun.