CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.367.20
Functional Family Hexokinase 1

Enzyme Information

2.7.1.2
Glucokinase.
based on mapping to UniProt P35557
ATP + D-glucose = ADP + D-glucose 6-phosphate.
-!- A group of enzymes found in invertebrates and microorganisms highly specific for glucose.

UniProtKB Entries (1)

P35557
HXK4_HUMAN
Homo sapiens
Glucokinase

PDB Structure

PDB 3H1V
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The design and optimization of a series of 2-(pyridin-2-yl)-1H-benzimidazole compounds as allosteric glucokinase activators.
Takahashi, K., Hashimoto, N., Nakama, C., Kamata, K., Sasaki, K., Yoshimoto, R., Ohyama, S., Hosaka, H., Maruki, H., Nagata, Y., Eiki, J., Nishimura, T.
Bioorg.Med.Chem.