CATH Classification

Domain Context

CATH Clusters

Superfamily Ubiquinol cytochrome reductase, transmembrane domain
Functional Family Cytochrome b-c1 complex subunit Rieske, mitochondrial

Enzyme Information

7.1.1.8
Quinol--cytochrome-c reductase.
based on mapping to UniProt Q5ZLR5
Quinol + 2 ferricytochrome c(Side 2) = quinone + 2 ferrocytochrome c(Side 2) + 2 H(+)(Side 2).
-!- The enzyme, often referred to as the cytochrome bc1 complex or complex III, is the third complex in the electron transport chain. -!- It is present in the mitochondria of all aerobic eukaryotes and in the inner membranes of most bacteria. -!- The mammalian enzyme contains cytochromes b-562, b-566 and c(1), and a 2-iron ferredoxin. -!- Depending on the organism and physiological conditions, the enzyme extrudes either two or four protons from the cytoplasmic to the non- cytoplasmic compartment (cf. EC 1.6.99.3). -!- Formerly EC 1.10.2.2.

UniProtKB Entries (1)

Q5ZLR5
UCRI_CHICK
Gallus gallus
Cytochrome b-c1 complex subunit Rieske, mitochondrial

PDB Structure

PDB 3H1J
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Electron Transfer by Domain Movement in Cytochrome Bc1
Zhang, Z., Huang, L.-S., Shulmeister, V.M., Chi, Y.I., Kim, K.K., Hung, L.W., Crofts, A.R., Berry, E.A., Kim, S.-H.
Nature