CATH Classification

Domain Context

CATH Clusters

Superfamily Nucleoside diphosphate kinase-like domain
Functional Family Nucleoside diphosphate kinase

Enzyme Information

2.7.4.6
Nucleoside-diphosphate kinase.
based on mapping to UniProt P22887
ATP + nucleoside diphosphate = ADP + nucleoside triphosphate.
-!- Many nucleoside diphosphates can act as acceptors. -!- Many ribo- and deoxyribonucleoside triphosphates can act as donors.

UniProtKB Entries (1)

P22887
NDKC_DICDI
Dictyostelium discoideum
Nucleoside diphosphate kinase, cytosolic

PDB Structure

PDB 3FKB
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Nucleoside diphosphate kinase and the activation of antiviral phosphonate analogs of nucleotides: binding mode and phosphorylation of tenofovir derivatives
Koch, K., Chen, Y.X., Feng, J.Y., Borroto-Esoda, K., Deville-Bonne, D., Gallois-Montbrun, S., Janin, J., Morera, S.
Nucleosides Nucleotides Nucleic Acids