CATH Classification

Domain Context

CATH Clusters

Superfamily Tyrosyl-Transfer RNA Synthetase
Functional Family Tryptophan--tRNA ligase

Enzyme Information

6.1.1.2
Tryptophan--tRNA ligase.
based on mapping to UniProt P00953
ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + L-tryptophyl- tRNA(Trp).

UniProtKB Entries (1)

P00953
SYW_GEOSE
Geobacillus stearothermophilus
Tryptophan--tRNA ligase

PDB Structure

PDB 3FHJ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Independent saturation of three TrpRS subsites generates a partially assembled state similar to those observed in molecular simulations.
Laowanapiban, P., Kapustina, M., Vonrhein, C., Delarue, M., Koehl, P., Carter, C.W.
Proc.Natl.Acad.Sci.Usa