CATH Classification

Domain Context

CATH Clusters

Superfamily SET domain
Functional Family Histone-lysine N-methyltransferase

Enzyme Information

2.1.1.43
Histone-lysine N-methyltransferase.
based on mapping to UniProt Q9NQR1
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].
2.1.1.-
Methyltransferases.
based on mapping to UniProt Q9NQR1

UniProtKB Entries (1)

P62805
H4_HUMAN
Homo sapiens
Histone H4

PDB Structure

PDB 3F9Z
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural origins for the product specificity of SET domain protein methyltransferases.
Couture, J.F., Dirk, L.M., Brunzelle, J.S., Houtz, R.L., Trievel, R.C.
Proc.Natl.Acad.Sci.Usa