CATH Classification

Domain Context

CATH Clusters

Superfamily Glutaredoxin
Functional Family Disulfide-isomerase A3

Enzyme Information

5.3.4.1
Protein disulfide-isomerase.
based on mapping to UniProt P30101
Catalyzes the rearrangement of -S-S- bonds in proteins.
-!- Needs reducing agents or partly reduced enzyme; the reaction depends on sulfhydryl-disulfide interchange.

UniProtKB Entries (1)

P30101
PDIA3_HUMAN
Homo sapiens
Protein disulfide-isomerase A3

PDB Structure

PDB 3F8U
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Insights into MHC class I peptide loading from the structure of the tapasin-ERp57 thiol oxidoreductase heterodimer.
Dong, G., Wearsch, P.A., Peaper, D.R., Cresswell, P., Reinisch, K.M.
Immunity