CATH Classification

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family Immunoglobulin kappa chain variable 12-38

Enzyme Information

UniProtKB Entries (1)

P20701
ITAL_HUMAN
Homo sapiens
Integrin alpha-L

PDB Structure

PDB 3EOB
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Efalizumab binding to the LFA-1 alphaL I domain blocks ICAM-1 binding via steric hindrance.
Li, S., Wang, H., Peng, B., Zhang, M., Zhang, D., Hou, S., Guo, Y., Ding, J.
Proc.Natl.Acad.Sci.USA