CATH Classification

Domain Context

CATH Clusters

Superfamily Aspartate Aminotransferase, domain 1
Functional Family Kynureninase

Enzyme Information

3.7.1.3
Kynureninase.
based on mapping to UniProt Q16719
L-kynurenine + H(2)O = anthranilate + L-alanine.
-!- Also acts on 3'-hydroxykynurenine and some other (3-arylcarbonyl)- alanines.

UniProtKB Entries (1)

Q16719
KYNU_HUMAN
Homo sapiens
Kynureninase

PDB Structure

PDB 3E9K
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of the Homo sapiens kynureninase-3-hydroxyhippuric acid inhibitor complex: insights into the molecular basis of kynureninase substrate specificity.
Lima, S., Kumar, S., Gawandi, V., Momany, C., Phillips, R.S.
J.Med.Chem.