CATH Classification

Domain Context

CATH Clusters

Superfamily D-amino Acid Aminotransferase, subunit A, domain 2
Functional Family Branched-chain-amino-acid aminotransferase

Enzyme Information

2.6.1.42
Branched-chain-amino-acid transaminase.
based on mapping to UniProt A0R066
L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate.
-!- Also acts on L-isoleucine and L-valine. -!- Different from EC 2.6.1.66.

UniProtKB Entries (1)

A0R066
ILVE_MYCS2
Mycolicibacterium smegmatis MC2 155
Branched-chain-amino-acid aminotransferase

PDB Structure

PDB 3DTG
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural analysis of mycobacterial branched chain aminotransferase - implications for inhibitor design
Castell, A., Unge, T.
To be Published