CATH Classification

Domain Context

CATH Clusters

Superfamily SH3 Domains
Functional Family Tyrosine-protein kinase Fyn

Enzyme Information

2.7.10.2
Non-specific protein-tyrosine kinase.
based on mapping to UniProt Q05876
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
-!- Unlike EC 2.7.10.1, this protein-tyrosine kinase does not have a transmembrane domain. -!- In the human genome, 32 non-specific protein-tyrosine kinases have been identified and these can be divided into 10 families. -!- Formerly EC 2.7.1.112.

UniProtKB Entries (1)

Q05876
FYN_CHICK
Gallus gallus
Tyrosine-protein kinase Fyn

PDB Structure

PDB 3CQT
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Theoretical and experimental demonstration of the importance of specific nonnative interactions in protein folding.
Zarrine-Afsar, A., Wallin, S., Neculai, A.M., Neudecker, P., Howell, P.L., Davidson, A.R., Chan, H.S.
Proc.Natl.Acad.Sci.Usa