CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.1190.20
Functional Family Phosphofructokinase

Enzyme Information

2.7.1.11
6-phosphofructokinase.
based on mapping to UniProt P06999
ATP + D-fructose 6-phosphate = ADP + D-fructose 1,6-bisphosphate.
-!- D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors. -!- UTP, CTP and ITP can act as donors. -!- Not identical with EC 2.7.1.105.

UniProtKB Entries (1)

P06999
PFKB_ECOLI
Escherichia coli K-12
ATP-dependent 6-phosphofructokinase isozyme 2

PDB Structure

PDB 3CQD
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystallographic structure of phosphofructokinase-2 from Escherichia coli in complex with two ATP molecules. Implications for substrate inhibition.
Cabrera, R., Ambrosio, A.L., Garratt, R.C., Guixe, V., Babul, J.
J.Mol.Biol.