CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.70.100
Functional Family copper-transporting ATPase 1

Enzyme Information

7.2.2.8
P-type Cu(+) transporter.
based on mapping to UniProt Q04656
ATP + H(2)O + Cu(+)(Side 1) = ADP + phosphate + Cu(+)(Side 2).
-!- A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. -!- This enzyme transports Cu(+) or Ag(+), and cannot transport the divalent ions, contrary to EC 7.2.2.9, which mainly transports the divalent copper ion. -!- Formerly EC 3.6.3.54.

UniProtKB Entries (1)

O00244
ATOX1_HUMAN
Homo sapiens
Copper transport protein ATOX1

PDB Structure

PDB 3CJK
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Copper(I)-mediated protein-protein interactions result from suboptimal interaction surfaces.
Banci, L., Bertini, I., Calderone, V., Della-Malva, N., Felli, I.C., Neri, S., Pavelkova, A., Rosato, A.
Biochem.J.