1 keywords

CATH Domain 3cdeA02

CATH Classification

Domain Context

CATH Clusters

Superfamily
Functional Family -

PDB Structure

PDB 3CDE
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda(6)-benzo[1',2',4']thiadiazin-3'-yl)-5-hydroxy-2H-pyridazin-3-ones. Part 3: Further optimization of the 2-, 6-, and 7'-substituents and initial pharmacokinetic assessments.
Li, L.S., Zhou, Y., Murphy, D.E., Stankovic, N., Zhao, J., Dragovich, P.S., Bertolini, T., Sun, Z., Ayida, B., Tran, C.V., Ruebsam, F., Webber, S.E., Shah, A.M., Tsan, M., Showalter, R.E., Patel, R., Lebrun, L.A., Bartkowski, D.M., Nolan, T.G., Norris, D.A., Kamran, R., Brooks, J., Sergeeva, M.V., Kirkovsky, L., Zhao, Q., Kissinger, C.R.
Bioorg.Med.Chem.Lett.