CATH Classification

Domain Context

CATH Clusters

Superfamily 2.80.10.50
Functional Family

Enzyme Information

3.2.2.22
rRNA N-glycosylase.
based on mapping to UniProt P33183
Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA.
-!- Ricin A-chain and related toxins show this activity. -!- Naked rRNA is attacked more slowly than rRNA in intact ribosomes. -!- Naked rRNA from Escherichia coli is cleaved at a corresponding position.

UniProtKB Entries (1)

P33183
NIGB_SAMNI
Sambucus nigra
Nigrin b

PDB Structure

PDB 3CAH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis for sugar recognition, including the Tn carcinoma antigen, by the lectin SNA-II from Sambucus nigra
Maveyraud, L., Niwa, H., Guillet, V., Svergun, D.I., Konarev, P.V., Palmer, R.A., Peumans, W.J., Rouge, P., Van Damme, E.J., Reynolds, C.D., Mourey, L.
Proteins