CATH Classification

Domain Context

CATH Clusters

Superfamily 2.60.120.200
Functional Family Botulinum neurotoxin type A

Enzyme Information

3.4.24.69
Bontoxilysin.
based on mapping to UniProt P0DPI1
Limited hydrolysis of proteins of the neuroexocytosis apparatus, synaptobrevins, SNAP25 or syntaxin. No detected action on small molecule substrates.
-!- Belongs to peptidase family M27.

UniProtKB Entries (1)

P0DPI1
BXA1_CLOBH
Clostridium botulinum A str. Hall
Botulinum neurotoxin type A

PDB Structure

PDB 3BTA
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of botulinum neurotoxin type A and implications for toxicity.
Lacy, D.B., Tepp, W., Cohen, A.C., DasGupta, B.R., Stevens, R.C.
Nat.Struct.Biol.