CATH Classification

Domain Context

CATH Clusters

Superfamily pyruvate carboxylase f1077a mutant domain
Functional Family Pyruvate carboxylase

Enzyme Information

6.4.1.1
Pyruvate carboxylase.
based on mapping to UniProt P11498
ATP + pyruvate + HCO(3)(-) = ADP + phosphate + oxaloacetate.
-!- The animal enzyme requires acetyl-CoA.

UniProtKB Entries (1)

P11498
PYC_HUMAN
Homo sapiens
Pyruvate carboxylase, mitochondrial

PDB Structure

PDB 3BG9
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structures of human and Staphylococcus aureus pyruvate carboxylase and molecular insights into the carboxyltransfer reaction.
Xiang, S., Tong, L.
Nat.Struct.Mol.Biol.