1 keywords

CATH Domain 3bejA00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.565 Retinoid X Receptor
Homologous Superfamily 1.10.565.10 Retinoid X Receptor

Domain Context

CATH Clusters

Superfamily Retinoid X Receptor
Functional Family Bile acid receptor isoform 4

Enzyme Information

UniProtKB Entries (1)

Q96RI1
NR1H4_HUMAN
Homo sapiens
Bile acid receptor

PDB Structure

PDB 3BEJ
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Identification of a potent synthetic FXR agonist with an unexpected mode of binding and activation.
Soisson, S.M., Parthasarathy, G., Adams, A.D., Sahoo, S., Sitlani, A., Sparrow, C., Cui, J., Becker, J.W.
Proc.Natl.Acad.Sci.Usa