CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family Elongation factor Tu

Enzyme Information

2.7.7.48
RNA-directed RNA polymerase.
based on mapping to UniProt P14647
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).
-!- Catalyzes RNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. -!- Can initiate a chain de novo. -!- See also EC 2.7.7.6.

UniProtKB Entries (1)

P0A6N3
EFTU_ECO57
Escherichia coli O157:H7
Elongation factor Tu

PDB Structure

PDB 3AVW
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Molecular basis for RNA polymerization by Q beta replicase
Takeshita, D., Tomita, K.
Nat.Struct.Mol.Biol.