CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family Casein kinase II subunit alpha

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt P68400
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

P68400
CSK21_HUMAN
Homo sapiens
Casein kinase II subunit alpha

PDB Structure

PDB 2ZJW
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural insight into human CK2alpha in complex with the potent inhibitor ellagic acid
Sekiguchi, Y., Nakaniwa, T., Kinoshita, T., Nakanishi, I., Kitaura, K., Hirasawa, A., Tsujimoto, G., Tada, T.
Bioorg.Med.Chem.Lett.