CATH Classification

Domain Context

CATH Clusters

Superfamily 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1
Functional Family Lactoylglutathione lyase

Enzyme Information

4.4.1.5
Lactoylglutathione lyase.
based on mapping to UniProt Q9CPU0
(R)-S-lactoylglutathione = glutathione + methylglyoxal.
-!- Also acts on 3-phosphoglycerol-glutathione.

UniProtKB Entries (1)

Q9CPU0
LGUL_MOUSE
Mus musculus
Lactoylglutathione lyase

PDB Structure

PDB 2ZA0
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The identification of an osteoclastogenesis inhibitor through the inhibition of glyoxalase I
Kawatani, M., Okumura, H., Honda, K., Kanoh, N., Muroi, M., Dohmae, N., Takami, M., Kitagawa, M., Futamura, Y., Imoto, M., Osada, H.
Proc.Natl.Acad.Sci.Usa