CATH Classification

Domain Context

CATH Clusters

Superfamily ATP-grasp fold, A domain
Functional Family

Enzyme Information

6.3.2.4
D-alanine--D-alanine ligase.
based on mapping to UniProt Q5SHZ3
ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine.
-!- Involved with EC 6.3.2.7 or EC 6.3.2.13, EC 6.3.2.8, EC 6.3.2.9 and EC 6.3.2.10 in the synthesis of a cell-wall peptide.

UniProtKB Entries (1)

Q5SHZ3
DDL_THET8
Thermus thermophilus HB8
D-alanine--D-alanine ligase

PDB Structure

PDB 2YZN
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of D-alanine:D-Alanine Ligase with AMPPNP from Thermus thermophilus HB8
Kitamura, Y., Yokoyama, S., Kuramitsu, S.
To be Published