CATH Classification

Domain Context

CATH Clusters

Superfamily Zinc/RING finger domain, C3HC4 (zinc finger)
Functional Family Histone-lysine N-methyltransferase 2C

Enzyme Information

2.1.1.43
Histone-lysine N-methyltransferase.
based on mapping to UniProt Q8NEZ4
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].

UniProtKB Entries (1)

Q8NEZ4
KMT2C_HUMAN
Homo sapiens
Histone-lysine N-methyltransferase 2C

PDB Structure

PDB 2YSM
External Links
Method SOLUTION NMR
Organism
Primary Citation
Solution structure of the first and second PHD domain from Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog
Qin, X.R., Hayashi, F., Yokoyama, S.
To be Published