CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.60.220
Functional Family Probable ATP-dependent RNA helicase DDX59

Enzyme Information

3.6.4.13
RNA helicase.
based on mapping to UniProt Q5T1V6
ATP + H(2)O = ADP + phosphate.
-!- RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. -!- Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity. -!- Some helicases unwind DNA as well as RNA. -!- May be identical with EC 3.6.4.12 (DNA helicase).

UniProtKB Entries (1)

Q5T1V6
DDX59_HUMAN
Homo sapiens
Probable ATP-dependent RNA helicase DDX59

PDB Structure

PDB 2YQP
External Links
Method SOLUTION NMR
Organism
Primary Citation
Solution structure of the zf-HIT domain in DEAD (Asp-Glu-Ala-Asp) box polypeptide 59
He, F., Muto, Y., Inoue, M., Kigawa, T., Shirouzu, M., Tarada, T., Yokoyama, S.
To be Published