CATH Classification

Domain Context

CATH Clusters

Superfamily ArgJ beta chain, C-terminal domain
Functional Family Arginine biosynthesis bifunctional protein ArgJ

Enzyme Information

2.3.1.35
Glutamate N-acetyltransferase.
based on mapping to UniProt P0DJQ5
N(2)-acetyl-L-ornithine + L-glutamate = L-ornithine + N-acetyl-L- glutamate.
-!- Also has some hydrolytic activity on acetyl-L-ornithine, but the rate is 1% of that of transferase activity.
2.3.1.1
Amino-acid N-acetyltransferase.
based on mapping to UniProt P0DJQ5
Acetyl-CoA + L-glutamate = CoA + N-acetyl-L-glutamate.
-!- Also acts with L-aspartate and, more slowly, with some other amino acids.

UniProtKB Entries (1)

P0DJQ5
GNAT2_STRCL
Streptomyces clavuligerus
Glutamate N-acetyltransferase 2

PDB Structure

PDB 2YEP
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural and Biochemical Analyses Reveal How Ornithine Acetyl Transferase Binds Acidic and Basic Amino Acid Substrates.
Iqbal, A., Clifton, I.J., Chowdhury, R., Ivison, D., Domene, C., Schofield, C.J.
Org.Biomol.Chem.