CATH Classification

Domain Context

CATH Clusters

Superfamily alpha/beta hydrolase
Functional Family Acetylcholinesterase

Enzyme Information

3.1.1.8
Cholinesterase.
based on mapping to UniProt P06276
An acylcholine + H(2)O = choline + a carboxylate.
-!- Acts on a variety of choline esters and a few other compounds.

UniProtKB Entries (1)

P06276
CHLE_HUMAN
Homo sapiens
Cholinesterase

PDB Structure

PDB 2XMC
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
X-Ray Crystallographic Snapshots of Reaction Intermediates in the G117H Mutant of Human Butyrylcholinesterase, a Nerve Agent Target Engineered Into a Catalytic Bioscavenge
Nachon, F., Carletti, E., Wandhammer, M., Nicolet, Y., Schopfer, L.M., Masson, P., Lockridge, O.
Biochem.J.